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Week 16 Preview: San Fransisco 49ers at Arizona Cardinals

Previewing the match-up between the San Francisco 49ers visiting the Arizona Cardinals, focusing on key injuries and game notes.



MIN @ NO | TB @ DET | SF @ ARZ | MIA @ LV | NYG @ BAL | ATL @ KC | CLE @ NYJ | CHI @ JAX

San Fransisco 49ers @ Arizona Cardinals
When: 12/26 @ 4:30pm ET
Watch: Prime Video
Point Spread: 49ers +5
Over/Under: 48.5
Moneyline: Cardinals -255 | 49ers +195

49ers Key Injuries: Jimmie Ward, FS, Concussion (O), Richard Sherman, CB, Calf (O), Deebo Samuel, WR, Hamstring (O), Jimmy Garoppolo, QB, Ankle (IR), Raheem Mostert, RB, Ankle (IR), Nick Mullens, QB, Elbow (IR), Javon Kinlaw, DT, Knee (Q), Hroniss Grasu, C, Knee (Q), Ben Garland, C, Calf (IR), George Kittle, TE, Foot (IR), Dee Ford, DE, Neck (IR), Ezekiel Ansah, DE, Biceps (IR), Nick Bosa, DE, ACL (IR), Soloman Thomas, DE, ACL (IR)
Cardinals Key Injuries: Dan Arnold, TE, Back (Q), Larry Fitzgerald, WR, Groin (Q), Hasson Reddick, OLB, Shoulder (Q), Chase Edmonds, RB, Ankle (Q), Dre Kirkpatrick, CB, Hamstring (Q), Justin Pugh, G, Calf (Q), Jalen Thompson, FS, Ankle (Q), Zane Gonzalez, K, Back (IR), Chandler Jones, LB, Biceps (IR)

Notes: The San Fransisco 49ers have been destroyed with injuries throughout the season and it has only gotten worse. Both Raheem Mostert and Nick Mullens will be done for the year. San Fran will now turn to their third quarterback this season, C.J. Bethard, who is nothing special. The Niners will be getting George Kittle back after missing about two months with an ankle injury. However, after losing their last three and the most disappointing loss coming off to Dallas this past week, there is not much left to say about Niners this season. They’ll look to salvage what they can but that’ll be a tough task against the Arizona Cardinals.

The Arizona Cardinals were off to a hot start at the beginning of the season. They started off 5-2 with key wins over the Seahawks and 49ers. After their bye week however, the spark wore off and they lost three in a row at one point. They now stand at 8-6, which is third in division but still within range of earning a wild card spot. Kyler Murray has continued to be stellar, especially against Philadelphia last week. Budda Baker has been stellar on the defensive end. He is currently sixth in the league in tackles. This game against the 49ers should be fairly favorable for Arizona. This game will be key for them as they continue their push for the playoffs.

Ethan was born and raised in Mount Laurel, New Jersey, right outside of Philadelphia. He's a sophomore at the University of Oregon studying journalism. He is an avid follower of the NFL, NBA, MLB, NHL, NCAA, and UFC. Since the return of sports, he has glued his eyes open only to experience continuous failure amongst his Philadelphia sports team.

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